Retatrutide Acetate (LY3437943)
| Attribute | Detail |
|---|---|
| Catalog No. | [Insert Product Number Here] |
| Purity | >98% (Third-Party Tested HPLC/MS) |
| Form | Lyophilized Powder |
| Quantity | 2mg, 5mg, or 10mg [Select appropriate size] |
| CAS Number | 2381089-83-2 |
⚠️ FOR LABORATORY RESEARCH USE ONLY ⚠️
This product is a research chemical intended strictly for in vitro and ex vivo laboratory experimentation. It is explicitly labeled "Not For Human Consumption." We do not sell to patients.
Product Description
Retatrutide (LY3437943) is a synthetic peptide being investigated as a "triple agonist" targeting the GLP-1, GIP, and glucagon receptors. This approach is being studied in preclinical and clinical settings for its effects on metabolism.
Scientific Research Applications
Retatrutide is a focus of current metabolic disease research. Scientists are using this compound in laboratory models to investigate weight management and glycemic control strategies.
Key research areas include:
- Multi-Hormonal Agonism: Research explores the synergistic metabolic effects of simultaneously activating GLP-1, GIP, and glucagon receptor pathways compared to single or dual agonists in research models.
- Appetite and Satiety: Studies investigate how Retatrutide may reduce food intake and promote fullness in animal models by acting on satiety centers.
- Energy Expenditure: Activation of the glucagon receptor is being studied for its role in fat metabolism and potential increase in energy expenditure in experimental subjects.
- Glucose Regulation: Researchers investigate how Retatrutide impacts glucose tolerance and insulin sensitivity, making it relevant for studies on type 2 diabetes and metabolic dysfunction-associated steatotic liver disease (MASLD/NAFLD).
Technical Specifications
- Sequence: The sequence is Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-MeL-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂
- Molecular Formula: C₂₂₁H₃₄₂N₄₆O₆₈ (free acid basis)
- Storage: Store lyophilized powder refrigerated (2°C - 8°C). Reconstituted solutions should be used promptly or stored refrigerated short-term following sterilization procedures.
Important Regulatory & Safety Information
- Investigational Status: Retatrutide is an investigational drug in Phase 3 clinical trials developed by Eli Lilly and Company. It is not FDA-approved or a dietary supplement.
- Strictly Research Use: This product is sold for non-clinical research and laboratory applications only. In vivo use in humans or animals is prohibited.
- Purchaser Responsibility: Buyers must be qualified researchers and assume all liability for proper use, handling, and compliance with applicable regulations for research chemicals.
