Tirzepatide Acetate (GIP/GLP-1 Dual Agonist, LY3298176)
| Attribute | Detail |
|---|---|
| Catalog No. | [Insert Product Number Here] |
| Purity | >98% (Third-Party Tested HPLC/MS) |
| Form | Lyophilized Powder |
| Quantity | 2mg, 5mg, or 10mg [Select appropriate size] |
| CAS Number | 1415456-99-3 |
⚠️ FOR LABORATORY RESEARCH USE ONLY ⚠️
This product is a research chemical intended strictly for in vitro and ex vivo laboratory experimentation. It is explicitly labeled "Not For Human Consumption."
Product Description
Tirzepatide is a synthetic polypeptide and a first-in-class dual agonist for both the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor. This unique "twincretin" structure consists of 39 amino acids with modifications, including a C20 fatty diacid moiety attached to the lysine residue at position 20, which increases albumin binding and prolongs its half-life for sustained research effects in animal models.
Scientific Research Applications
Tirzepatide is a major focus in metabolic and endocrinology research due to its potent effects observed in preclinical and clinical studies (Note: the research chemical form is not approved). Researchers use it to investigate mechanisms related to glycemic control and body weight regulation in experimental models.
Key research areas include:
- Dual Receptor Mechanism: Studies investigate how the combined activation of GIP and GLP-1 receptors enhances insulin secretion and suppresses glucagon release in a glucose-dependent manner in laboratory models.
- Metabolic Regulation: Research in animal models explores Tirzepatide's effects on reducing food intake, slowing gastric emptying, and decreasing body weight, plasma leptin, and triglyceride levels.
- Insulin Sensitivity: Investigations focus on the peptide's ability to improve insulin sensitivity and secretion responses in experimental subjects compared to single-agonist treatments.
Technical Specifications
- Sequence: Refer to complex sequence diagram, but generally described as 39-amino acid linear polypeptide with C20 fatty diacid conjugation
- Molecular Formula: C225H348N48O68
- Storage: Store lyophilized powder refrigerated (2°C - 8°C). Protect from light and moisture.
Important Regulatory & Safety Information
- Investigational/Unapproved Drug: Tirzepatide (brand names Mounjaro, Zepbound) is an FDA-approved prescription medication for specific human conditions (Type 2 diabetes and weight management). This research-grade chemical version, however, is not the FDA-approved product and is sold strictly for laboratory research. The FDA has warned against purchasing illegally marketed versions labeled "for research purposes" for human use.
- Strictly Research Use: This product is sold solely for non-clinical research and development purposes. In vivo use in humans or animals outside of licensed research is prohibited.
- Purchaser Responsibility: By purchasing this product, the buyer acknowledges they are a qualified researcher and assumes all liability for the proper use, handling, and compliance with all applicable local, state, and federal laws and regulations regarding research chemicals.
